Just picked up Imoen in Spellhold with a virtue of 19 and rep of 20, but she keeps spouting her UNHAPPY_ANNOYED line of "I'll stick with you no matter what, but we should still try and be decent to people." line. I'm also using NG Jaheira from Tweaks and it would be nice if she tossed out Virtue lines to reflect this.
In Lady Galvena's festhall, you can use the sleeping drought to knock out the guards and get the key to the dungeon without violence. However, you can still kill the sleeping guards--while it can be argued that the guards are evil and/or helping evil, I think it's worth considering a virtue penalty here for unnecessary killing.